Animal mitochondrial DNA recombination
نویسندگان
چکیده
منابع مشابه
Animal mitochondrial DNA recombination revisited
Exchange of homologous sequences between mitochondrial DNA (mtDNA) molecules is thought to be absent in animals, primarily because of a failure to observe clear cases of recombinant haplotypes in natural populations. However, whether mtDNA recombination occurs is a different issue from whether it produces new haplotypes. A requirement for the latter is heteroplasmy – the presence of more than o...
متن کاملRecombination in animal mitochondrial DNA.
1 Rb7 . . . . . 2 Rn8 . . . . . 3 Rc6 . . . . . 4 Ra1 . . . . . 5 Rd5 . . . . . 6 Rd4 . . . . . 7 Rr2 . . . . . 8 Rr3 . . . . . AF205088 AF205087 AF205089 AF205094 AF205090 AF205091 AF205093 AF205092 R. plancyi R. nigromaculata R. catesbeiana R. amurensis R. dybowskii R. dybowskii R. rugosa R. rugosa Previous attempts to demonstrate, or refute, the occurrence of recombination in mitochondria ha...
متن کاملRecombination in animal mitochondrial DNA: evidence from published sequences.
The question of whether animal mitochondrial DNA (mtDNA) undergoes recombination has recently been the subject of intense debate. In a recent paper (Ladoukakis and Zouros 2001), we presented evidence for mtDNA recombination from direct recovery of recombinant molecules in the gonads of several males of the mussel Mytilus galloprovincialis. Because in this species there exist two lineages of mit...
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The field of mitochondrial DNA (mtDNA) replication has been experiencing incredible progress in recent years, and yet little is certain about the mechanism(s) used by animal cells to replicate this plasmid-like genome. The long-standing strand-displacement model of mammalian mtDNA replication (for which single-stranded DNA intermediates are a hallmark) has been intensively challenged by a new s...
متن کاملRecombination of human mitochondrial DNA.
Human mitochondrial DNA (mtDNA) is a 16.5-kb, circular genome essential for the maintenance of mitochondrial function and is present in multiple copies in most cell types. High sequence divergence and maternal inheritance make mtDNA useful in tracing human lineages. Whether recombination occurs between mitochondrial genomes is a longstanding question in mitochondrial biology, human evolution, a...
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ژورنال
عنوان ژورنال: Nature
سال: 1997
ISSN: 0028-0836,1476-4687
DOI: 10.1038/387247a0